Porphyrin–phospholipid liposomes permeabilized by near-infrared light
نویسندگان
چکیده
منابع مشابه
Porphyrin–phospholipid liposomes permeabilized by near-infrared light
The delivery of therapeutic compounds to target tissues is a central challenge in treating disease. Externally controlled drug release systems hold potential to selectively enhance localized delivery. Here we describe liposomes doped with porphyrin-phospholipid that are permeabilized directly by near-infrared light. Molecular dynamics simulations identified a novel light-absorbing monomer ester...
متن کاملNear‐infrared light‐sensitive liposomes for enhanced plasmid DNA transfection
Near-infrared (NIR) light-responsive liposomes are attractive carriers for targeted and controlled drug delivery to the superficial organ or tissue (e.g., skin). This work describes the development of NIR-responsive liposomes by incorporating gold nanostars within liposomes composed of Phospholipon 90 g and cholesterol. Following cellular delivery, photothermal effect around the gold nanostar u...
متن کاملNear-infrared light photoacoustic ophthalmoscopy
We achieved photoacoustic ophthalmoscopy (PAOM) imaging of the retina with near-infrared (NIR) light illumination. A PAOM imaging system with dual-wavelength illumination at 1064 nm and 532 nm was built. We compared in vivo imaging results of both albino and pigmented rat eyes at the two wavelengths. The results show that the bulk optical absorption of the retinal pigment epithelium (RPE) is on...
متن کاملApplication of near-infrared light intensity to determine normal and cancerous breast vessel contrast by gold nanoparticles
Objective(s): A novel technique for the early diagnosis of breast cancer involves the use of nanoparticles (NPs). The present study aimed to use gold NPs to assess the variations in light source transfer intensity. Materials and Methods: Blood samples with hemoglobin (Hb) concentrations of ×1, ×2, and ×4 were used to simulate normal and cancerous conditions in the breast. Spherical gold N...
متن کاملNear-infrared light scattering by particles in coastal waters.
We report the first measurements of the scattering coefficient of natural marine particles, which extend over the near-infrared spectral region to up to 870 nm. The measurements were conducted in three different European estuaries (Gironde, Tamar and Elbe) using an in situ absorption and attenuation-meter. The observed particulate scattering coefficients varied from 1 to nearly 100 m(-1). The s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Communications
سال: 2014
ISSN: 2041-1723
DOI: 10.1038/ncomms4546